Services Effectiveness Research Program (SERP)
Duke University School of Medicine
Department of Psychiatry and Behavioral Sciences
Henry Ryan Wagner II, Ph.D.
Associate Professor of Psychiatry and Behavioral Sciences
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|| Box 3454 DUMC Durham, NC 27710
1967 UCLA B.S. Business Administration
1975 University of New Mexico Ph.D. Experimental Psychology
1979 Duke University Postdoctoral Neuropharmacology
1998 Duke University M.H.S. (abt) Biometry
Program for Assertive Community Treatment (PACT): As an extension of studies into the effect of Assertive Community Treatment Programs on client outcomes, family burdens, service mix, and costs, we are extending our work to a meta-analysis of outcomes using data from five just-completed PACT studies at geographically diverse sites throughout the U.S. As existing research has suggested that a major point of impact of PACTs is on institutionalization, we will initially focus our analyses on psychiatric hospital admissions and hospital days. Interest is in (1) determining if PACTs effectively reduce admissions and days relative to state-of-the-art community mental health programs and (2) if so, are reductions associated with patient characteristics including age, race, sex, and diagnosis.
Outpatient Commitment Programs (OPC): Data collection and management continue on a study of the effects of outpatient commitment on client outcomes, compliance, and family burden among the severely and persistently mentally ill (SPMI). Substantial recruitment has already occurred allowing the possibility of panel analyses of the baseline profile of the sample. Questions of interest include sex and race differences in quality-of-life indices, social interactions, social networks, and diagnosis. We are also exploring the possibility of combining these data with a similar study sampel recruited for a study of PACT programs in Charleston, S.C. The two studies share considerable common information; combined analyses would expand the base of inference and provide a marked increase in power necessary for assessment of often highly variable psychosocial outcomes.
Somatic Manifestations of Depression: We are continuing to investigate the association between CES-D scores and mortality. Using a geriatric sample, we have demonstrated a positive association between CES-D scores and mortality over a five year interval. Current efforts are directed at refining the association between CES-D scores and the appearance of various disease states over the same interval. We continue to hypothesize a relationship between depression and impaired immune function as operationalized in the disproportionate incidence of infectious diseases and neoplastic events.
Barbara J. Burns, Susan D. Phillips, H. Ryan Wagner, Richard Barth, David J. Kolko, Yvonne Cambell, and John Landsverk (2004). Mental Health Need and Access to Mental Health Services by Youths Involved With Child Welfare: A National Survey.Journal of the American Acadamey of Child and Adolescent Psychiatry. Vol. 43, No. 8: 960-970.
Barbara J. Burns, Susan D. Phillips, H. Ryan Wagner, Richard Barth, David J. Kolko, Yvonne Cambell, and John Landsverk (2004). Journal of the American Acadamey of Child and Adolescent Psychiatry. Vol. 43, No. 8: 960-970.
Morey RA, Selgrade ES, Wagner HR 2nd, Huettel SA, Wang L, McCarthy G. Scan-rescan reliability of subcortical brain volumes derived from automated segmentation. Hum Brain Mapp. 2010 Feb 16. Abstract
Morey RA, Petty CM, Xu Y, Hayes JP, Wagner HR 2nd, Lewis DV, LaBar KS, Styner M, McCarthy G. A comparison of automated segmentation and manual tracing for quantifying hippocampal and amygdala volumes. Neuroimage. 2009 Apr 15;45(3):855-66. Abstract
Morey RA, Petty CM, Xu Y, Hayes JP, Wagner HR 2nd, Lewis DV, Labar KS, Styner M, McCarthy G. Rebuttal to Hasan and Pedraza in comments and controversies: "Improving the reliability of manual and automated methods for hippocampal and amygdala volume measurements". Neuroimage. 2009 Nov 15;48(3):499-500. Abstract
Ulmer CS, Calhoun PS, Edinger JD, Wagner HR, Beckham JC. Sleep disturbance and baroreceptor sensitivity in women with posttraumatic stress disorder. J Trauma Stress. 2009 Dec;22(6):643-7. Abstract
Swanson JW, Swartz MS, Elbogen EB, VAN Dorn RA, Wagner HR, Moser LA, Wilder C, Gilbert AR. Psychiatric advance directives and reduction of coercive crisis interventions. J Ment Health. 2008 Jan 1;17(3):255-267. Abstract