Services Effectiveness Research Program (SERP)

Duke University School of Medicine
Department of Psychiatry and Behavioral Sciences

Current and Recent Projects

Title: Schizophrenia Care and Assessment Program (SCAP)

Sponsor: Eli Lilly and Company

Principal Investigator(s): Jeffrey Swanson, PhD; Marvin Swartz, MD

SERP Investigators & Collaborators: Richard Van Dorn, PhD

Project Description: The Schizophrenia Care and Assessment Program (SCAP) is a multi-site collaborative study funded by Eli Lilly and Company which examines the diffusion, effectiveness, and cost of new treatments for schizophrenia in several systems of care. The SCAP also develops a technology for standardized assessment and monitoring of treatment outcomes for persons with schizophrenia. The overall study is being coordinated by a private contractor, the MEDSTAT Group of Washington , D.C. Duke University Medical Center will subcontract to enroll a sample of 200 inpatients and 200 outpatients with schizophrenia spectrum disorders in North Carolina and collect data on their services utilization patterns and outcomes over a three year period. These data, with individual identifiers removed, will be pooled with comparable data from four other sites. The resulting large database (N=2,000 to 2,400) will provide a valuable resource for examining factors that affect the diffusion of new treatment technologies (e.g., olanzapine and other atypical antipsychotic medications), as well as associated outcomes and costs of care for persons with schizophrenia across a range of clinical practice settings, organizations, and health care financing structures. Investigators from DUMC will conduct the SCAP study locally among patients residing in Durham , Vance, Warren , Granville, and Franklin Counties . Subjects will be recruited at the following facilities: John Umstead Hospital , Duke Hospital , the Durham Veterans Administration Medical Center , Durham County Mental Health Center , and Vance-Warren-Granville-Franklin County Mental Health Center . Human subjects research review will occur at all participating recruitment sites. Methods of data collection will be limited to (1) questionnaires and structured interviews conducted in-person and/or by telephone with patients, family members, and clinicians; (2) electronic retrieval of data from health care management information systems on services utilization and costs; (3) review and abstraction of medical records.

SCAP will improve the quality of mental health care for schizophrenia by providing needed information on: (1) outcomes of care; (2) use of a broad range of treatments across differing care systems; (3) cost of these services; (4) diffusion of new technologies (e.g., atypical antipsychotic medications) into public and private care sectors; and (5) organizational characteristics of care settings in which schizophrenia care is provided.